发明名称 METHODS OF TREATING CANCER AND THE PAIN ASSOCIATED THEREWITHUSING ENDOTHELIN ANTAGONISTS
摘要 The instant invention is directed to methods for the inhibition of bone metastases, methods for the prevention of growth of new metastases, methods for the inhibition of bone turnover, and methods for the prevention of bone loss in patients, including cancer patients, using an endothelin ET-A recept or antagonist.
申请公布号 CA2416879(A1) 申请公布日期 2002.02.14
申请号 CA20012416879 申请日期 2001.08.06
申请人 ABBOTT LABORATORIES 发明人 JANUS, TODD J.;PADLEY, ROBERT J.
分类号 C07D405/04;A61K31/40;A61K31/4025;A61K31/415;A61K31/495;A61K31/565;A61K31/57;A61K31/59;A61K31/66;A61K31/663;A61K38/09;A61K38/16;A61K41/00;A61K45/00;A61K45/06;A61P3/02;A61P5/28;A61P5/30;A61P5/34;A61P5/44;A61P13/08;A61P19/08;A61P19/10;A61P25/04;A61P35/00;A61P35/04;A61P43/00;(IPC1-7):A61K31/00 主分类号 C07D405/04
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