This invention provides neuroprotective pharmaceutical compositions comprising 2-pyridinamines. This invention also provides methods of using these compositions to prevent ischemic cell death, particularly neuronal cell death, and reduce the likelihood of neuronal cell death in a subject due to a traumatic event. Finally, this invention provides an apparatus for administering to a subject the instant pharmaceutical compositions.
申请公布号
WO0211724(A2)
申请公布日期
2002.02.14
申请号
WO2001US41565
申请日期
2001.08.06
申请人
ORTHO-MCNEIL PHARMACEUTICAL, INC.
发明人
GRANT, ELFRIDA, R.;BROWN, FRANK, K.;ZIVIN, ROBERT, ALLAN;MCMILLAN, MICHAEL;ZHONG, ZHONG;BENJAMIN, DANIEL