Method and apparatus for predicting a signal peptide cleavage site

摘要

A method and apparatus for predicting a signal peptide cleavage site associated with an amino acid sequence is provided. The system determines a size (X+Y) for a scanning window based on a positive training data set and a negative training data set. The scanning window has a signal peptide portion of length X and a mature protein portion of length Y. The training data set is indicative of a plurality of amino acid sequences with known peptide cleavage sites. The method then scans the window across the amino acids from an amino acid sequence suspected of containing a signal peptide looking for the most likely cleavage site based on the training data.