New ribulose-phosphate 3-epimerase gene from coryneform bacteria, useful for transforming cells for improved fermentative production of L-amino acids, especially lysine

摘要

An isolated polynucleotide (I) from coryneform bacteria containing a sequence that: (a) is at least 70% identical to a sequence encoding a 219 amino acid (aa) polypeptide (II); (b) encodes a polypeptide (III) at least 70% identical with (II); (c) is complementary to (II) or (III); or (d) contains at least 15 consecutive bases from (I)-(III), is new An Independent claim is also included for a method (M) for producing L-aa, especially L-lysine, by fermenting coryneform bacteria in which the activity of the ribulose-phosphate 3-epimerase (rpe) gene, or its equivalent, is increased.