Process for the preparation of 9-amino substituted 9,10-dihydropyrrolo (2,1-B)(1,3)benzotiazepines

摘要

A process is described for the preparation of compounds with the following formula where the groups are as defined below; in particular, R₁ is a substituted amine; said process includes essentially the reaction of pyrrolobenzothiazepin-9-one with amine R₁H to give the corresponding enamine, which is subsequently transformed into the final compound