发明名称 Nucleic acid constructs and methods utilizing same for detecting anti-viral drugcandidates and for determining drug resistance of viral isolates
摘要 A nucleic acid construct is provided. The nucleic acid construct includes a polynucleotide cassette encoding a chimeric polypeptide including: (a) a first polypeptide sequence; (b) a second polypeptide sequence being translationally fused to the first polypeptide sequence; and (c) at least one protease recognition site being cleavable by a virally encoded protease, wherein cleavage of the at least one protease recognition site leads to a detectable signal.
申请公布号 AU8243701(A) 申请公布日期 2002.02.13
申请号 AU20010082437 申请日期 2001.07.30
申请人 AMIDUT LTD. 发明人 ELENA APPEL
分类号 C07K14/16;C12P21/04 主分类号 C07K14/16
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