摘要 |
A nucleic acid construct is provided. The nucleic acid construct includes a polynucleotide cassette encoding a chimeric polypeptide including: (a) a first polypeptide sequence; (b) a second polypeptide sequence being translationally fused to the first polypeptide sequence; and (c) at least one protease recognition site being cleavable by a virally encoded protease, wherein cleavage of the at least one protease recognition site leads to a detectable signal. |