发明名称 |
Method for producing enantiomer-free 6,8 dihydroxy octanoic acid esters by meansof asymmetric, catalytic hydrogenation |
摘要 |
The invention relates to a process for the preparation of compounds of the general formula I in which R<SUP>1 </SUP>represents a C<SUB>1</SUB>-C<SUB>20</SUB>-alkyl group, a C<SUB>3</SUB>-C<SUB>12</SUB>-cycloalkyl group, a C<SUB>7</SUB>-C<SUB>12</SUB>-aralkyl group or a mono- or bi-nuclear aryl group, in which a ketone of formula II wherein R<SUP>1 </SUP>is as defined above, is subjected to asymmetric hydrogenation. |
申请公布号 |
AU8763501(A) |
申请公布日期 |
2002.02.13 |
申请号 |
AU20010087635 |
申请日期 |
2001.07.17 |
申请人 |
ASTA MEDICA AKTIENGESELLSCHAFT |
发明人 |
RAINER GEWALD |
分类号 |
C07B53/00;C07B61/00;C07C67/31;C07C69/675;C07C69/716;C07D303/32;C07D303/40;C07D339/04 |
主分类号 |
C07B53/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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