| 摘要 |
The present invention concerns compositions and methods for analyzing, separating or sequencing nucleic acids. More particularly, it concerns methods for analyzing, separating or sequencing nucleic acids by electrophoresis, in particular capillary, more preferably gel-free. The invention also concerns methods for treating nucleic acids, or separating nucleic acids, applicable to rapid and efficient sequencing. The invention further concerns products, compositions and kits for implementing said methods. The invention consists particularly in the use of a positively charged carrier molecule, enabling to efficiently separate nucleic acids in solution. The invention is useful for analyzing, separating or sequencing nucleic acids of different type and origin, in the field of experimentation, diagnosis, medicine and the like, in particular de novo sequencing and genotyping. |
