发明名称 |
Isolation of drosophila and human polynucleotides encoding par-1 kinase, polypeptides encoded by the polynucleotides and methods utilizing the polynucleotides and polypeptides |
摘要 |
Isolated nucleic acid molecules comprising polynucleotide having sequences that encode human and Drosophila PAR-1 kinases. Also provided are proteins and polypeptides encoded by the nucleic acid molecules, methods of modulating PAR-1 expression and function, and methods of modulating the Wnt signaling pathway. |
申请公布号 |
AU7910601(A) |
申请公布日期 |
2002.02.13 |
申请号 |
AU20010079106 |
申请日期 |
2001.07.30 |
申请人 |
CHIRON CORPORATION |
发明人 |
TIAN-QIANG SUN;JIA-JIA FENG;CHRISTOPH REINHARD;WENDY J. FANTL;LEWIS T. WILLIAMS |
分类号 |
C12N15/09;A61K38/00;A61K38/46;A61K39/395;A61K45/00;A61K48/00;A61P35/00;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N9/12;C12N15/54;C12Q1/48;G01N33/573 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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