HAIR GROWTH AND RESTORATION PROMOTER

摘要

PROBLEM TO BE SOLVED: To obtain a hair growth and restoration promoter having secretion accelerating actions on a hepatocyte growth factor(HGF) having proliferation promoting actions on hair papillary cells or a hair growth promoting activity and further excellent hair growth and restoration promoting effects. SOLUTION: This hair growth and restoration promoter comprises a substance having serection accelerating actions on a physiologically active substance acting on a receptor having a specific affinity foe endothelin-1(ET-1) present in hair papillary cells, e.g. an ET-A receptor having high affinity for ET-1 and ET-2 and a nonselective ET-B receptor and having proliferation promoting actions on the hair papillary cells and/or the hair growth promoting actions such as the HGF, e.g. the ET-1, an ET-1 analog and an agonist of the receptors as an active ingredient. The cosmetic comprising the hair growth and restoration promoter formulated therein is prepared.