| 发明名称 |
Hydroxylation activated prodrugs |
| 摘要 |
The present invention concerns enzymatic aromatic hydroxylation-activated prodrugs, particularly anti-tumour prodrugs and those which are specifically activated by the hydroxylation activity of the enzyme CYP1B1.
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| 申请公布号 |
US6346550(B2) |
申请公布日期 |
2002.02.12 |
| 申请号 |
US20010765861 |
申请日期 |
2001.01.19 |
| 申请人 |
POTTER GERALD ANDREW;PATTERSON LAWRENCE HYLTON;BURKE MICHAEL DANNY |
发明人 |
POTTER GERALD ANDREW;PATTERSON LAWRENCE HYLTON;BURKE MICHAEL DANNY |
| 分类号 |
A61K31/085;A61K31/09;A61K31/12;A61K31/145;A61K31/275;A61K31/4406;A61K31/4418;A61P35/00;A61P43/00;C07C43/215;C07C49/84;C07C205/35;C07C255/36;C07C327/44;C07C327/48;C07D213/57;(IPC1-7):A61K31/12 |
主分类号 |
A61K31/085 |
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