发明名称 |
Streptomyces Avermitilis gen som bestemmer forholdet B2:B1 avermectiner |
摘要 |
<p>The present invention relates to polynucleotide molecules comprising nucleotide sequences encoding an aveC gene product, which polynucleotide molecules can be used to alter the ratio or amount of class 2:1 avermectins produced in fermentation cultures of S. avermitilis. The present invention further relates to vectors, host cells, and mutant strains of S. avermitilis in which the aveC gene has been inactivated, or mutated so as to change the ratio or amount of class 2:1 avermectins produced.</p> |
申请公布号 |
NO20020664(D0) |
申请公布日期 |
2002.02.11 |
申请号 |
NO20020000664 |
申请日期 |
2002.02.11 |
申请人 |
PFIZER PRODUCTS INC |
发明人 |
CHEN, YAN;GUSTAFSSON, CLAES;KREBBER, ANKE;MINSHULL, JEREMY STEPHEN;RAILLARD, SUN AI;STUTZMAN-ENGWALL, KIM JONELLE |
分类号 |
C12N15/09;C12N;C12N1/21;C12N9/88;C12N15/60;C12N15/76;C12P;C12P17/18;C12P19/44;C12P19/62;C12R;C12R1/465 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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