| 摘要 |
<p>The present invention provides antibodies that specifically bind with a high degree of binding affinity to a native ungulate PrPC in situ and/or a denatured ungulate PrPSc, but not to a native ungulate PrPSc in situ. Preferred antibodies bind native bovine PrPC and treated PrPSc but not native bovine PrPSc in situ and can be used in an assay to determine if a sample is infected with infectious prions, i.e. pathogenic PrPSc.</p> |
