发明名称 CATHEPSIN INHIBITORS IN CANCER TREATMENT
摘要 Embodiments of the present invention provide methods for inhibiting tumor cell growth, or treating cancer cells, in a subject through the administration of a cathepsin inhibitor or inhibitors. Methods for inhibiting inflammatory disease cells as well as other cathepsin expressing cells in a subject with a cathepsin inhibitor or inhibitors are also within the present invention. Furthermore, the present invention relates to inducing cytotoxicity or apoptosis in cells by administering a cytotoxic or an apoptotic dose of a cathepsin inhibitor or inhibitors to the cell. Finally, the present invention relates to the administering of cathepsin expressing vectors to tumor cells so as to inhibit the tumor cells growth.
申请公布号 WO0174376(A3) 申请公布日期 2002.02.07
申请号 WO2001US10196 申请日期 2001.03.30
申请人 PARKER HUGHES INSTITUTE;UCKUN, FATIH, M.;ZHU, DE-MIN 发明人 UCKUN, FATIH, M.;ZHU, DE-MIN
分类号 A61K38/00;A61K38/55;(IPC1-7):A61K38/06;A61K48/00;A61P35/00 主分类号 A61K38/00
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