发明名称 |
DIRECTED DIFFERENTIATION OF EMBRYONIC CELLS |
摘要 |
Methods are described for mapping a pathway of differentiation of a population of embryonic cells which includes exposing the cells to an exogenous factor and measuring gene expression products that are characteristic of a particular cell type or lineage. Directing differentiation of human embryonic cells relies on dissociated embryoid bodies which are then exposed to one or more exogenous factors to enrich a culture for a particular cell type. The differentiated cells may be used for treating a medical condition in a human. Kits for determining differentiation pathways and screening exogenous factors for their utility in differentiation are provided. |
申请公布号 |
WO0210347(A2) |
申请公布日期 |
2002.02.07 |
申请号 |
WO2001IB01719 |
申请日期 |
2001.07.31 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY |
发明人 |
BENVENISTY, NISSIM |
分类号 |
C12N15/09;A61K35/12;A61P1/16;A61P5/38;A61P7/06;A61P9/04;A61P13/12;A61P17/00;A61P25/00;A61P37/02;C12N5/073;C12N5/0793;C12N5/10;C12Q1/02;C12Q1/68;G01N33/50 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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地址 |
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