发明名称 |
Nonpeptide insulin receptor agonists |
摘要 |
Modulation of the activity of the insulin receptor, enhancement of glucose uptake by cells, and other effects significant in the control and management of diabetes are accomplished using compounds of the formula wherein each A is independently a proton-accepting substituent; each R is independently a noninterfering substituent; m is 0 or 1; n is 0, 1, or 2; and each linker is independently an isostere of -N=N- or of -NHCO-. Compounds in the genus of Formula (1) can also be used for structure activity studies to identify features responsible for the relevant activities.
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申请公布号 |
US2002016367(A1) |
申请公布日期 |
2002.02.07 |
申请号 |
US20010961179 |
申请日期 |
2001.09.21 |
申请人 |
SPORTSMAN RICHARD;VILLAR HUGO O.;KAUVAR LAWRENCE M.;SATYAM APPARAO |
发明人 |
SPORTSMAN RICHARD;VILLAR HUGO O.;KAUVAR LAWRENCE M.;SATYAM APPARAO |
分类号 |
C07C309/34;C12Q1/34;C12Q1/48;G01N33/58;G06F17/30;H04N5/445;(IPC1-7):A61K31/17;G01N33/53 |
主分类号 |
C07C309/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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