COMPOSITIONS EXHIBITING SYNERGISTIC INHIBITION OF THE EXPRESSION AND/OR ACTIVITY OF CYCLOOXYGENASE-2

摘要

A novel formulation is provided that serves to inhibit the inflammatory response in animals. The formulation comprises, as a first component, a diterpene triepoxide lactone species or a sesquiterpene lactone species and, as a second component, at least one member selected from the group consisting of a diterpene triepoxide lactone species, a sesquiterpene lactone species, a diterpene lactone species, and a triterpene species or derivatives thereof with the proviso that the same first component cannot also serve as the second component, and provides synergistic anti-inflammatory effects in response to physical or chemical injury or abnormal immune stimulation due to a biological agent or unknown etiology.