| 发明名称 |
PIPERAZINE DERIVATIVES |
| 摘要 |
The present invention refers to chemical compounds of formula (I) as well as pharmaceutically usable salts, solvates and esters thereof, wherein R1 to R8 have the significance given in claim 1. They can be used in the form of pharmaceutical preparations for the treatment or prevention of disorders of the central nervous system, damage to the central nervous system, cardiovascular disorders, gastrointestinal disorders, diabetes insipidus, obesity and sleep apnoea. |
| 申请公布号 |
CA2417106(A1) |
申请公布日期 |
2002.02.07 |
| 申请号 |
CA20012417106 |
申请日期 |
2001.07.24 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;VERNALIS RESEARCH LIMITED |
发明人 |
RICHTER, HANS;ROEVER, STEPHAN;HEBEISEN, PAUL;MULLER, MARC;BENTLEY, JONATHAN, MARK;MATTEI, PATRIZIO;TAYLOR, SVEN |
| 分类号 |
A61K31/337;A61K31/4985;A61K45/00;A61P1/00;A61P3/04;A61P3/10;A61P7/02;A61P9/00;A61P11/00;A61P13/00;A61P15/00;A61P25/00;A61P25/06;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/32;C07D487/04;(IPC1-7):C07D487/04;C07D241/00;A61K31/498;C07D209/00 |
主分类号 |
A61K31/337 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
