ANALYSIS OF BIOLOGICAL SAMPLES FOR PLATELET ACTIVATION OR COAGULATION ACTIVATION MARKERS USING MICROPARTICULES
摘要
The invention disclosed herein comprises methods for analyzing a biological sample, such as undiluted or diluted whole blood, as well as fractions thereof, for the presence or absence and/or the concentration of disease-specific and/or other medical condition-specific markers. Such markers may include platelet activation and coagulation activation markers. The methods may comprise combining the biological sample with a coated solid phase and analyzing for the presence or absence and/or the concentration of the markers. The analysis may be performed either before or after separation of the solid phase from the biological sample. The analysis may be performed on the combined components or an any of the separation components. A preferred solid phase may be paramagnetic microparticles coated with antibodies or proteins specific for platelet activation and/or coagulation activation markers.
申请公布号
WO0210771(A1)
申请公布日期
2002.02.07
申请号
WO2001US24132
申请日期
2001.08.01
申请人
CAREPOINT DIAGNOSTICS, INC.;HENRY, MICHAEL, R.;LEAHY, DAVID, C.;SHEBUSKI, RONALD, J.
发明人
HENRY, MICHAEL, R.;LEAHY, DAVID, C.;SHEBUSKI, RONALD, J.