| 发明名称 |
PHARMACOKINETIC AND PHARMACODYNAMIC MODELING OF ERYTHROPOIETIN ADMINISTRATION |
| 摘要 |
The present invention relates to systems and methods for obtaining optimized EPO dosage regimens for a desired pharmacodynamic/pharmacokinetic response. The system includes choosing one or more EPO dosage regimens, then using a PK/PD model to determine the pharmacodynamic/pharmacokinetic profile of one or more EPO dosage regimens, and finally selecting one of the EPO dosage regimens for administration to achieve the desired pharmacodynamic/pharmacodynamic response based on the EPO profile. |
| 申请公布号 |
EP1176975(A1) |
申请公布日期 |
2002.02.06 |
| 申请号 |
EP20000928933 |
申请日期 |
2000.05.10 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
CHEUNG, WING;PHILIPS, BART;GIBSON, DAVIS;COTE, CHRISTINE |
| 分类号 |
A61K38/00;A61K31/282;A61K31/7072;A61K33/24;A61K38/12;A61K38/18;A61K38/22;A61M37/00;A61P7/00;A61P7/06;A61P7/08;A61P13/12;A61P19/02;A61P29/00;A61P31/18;A61P35/00;A61P43/00;G06F19/00;G06Q10/00 |
主分类号 |
A61K38/00 |
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