发明名称 |
Fremgangsmåte for inhibering av amyloidprotein-aggregering og billeddannelse av amyloidavleiring ved bruk av isoindolin-derivater |
摘要 |
<p>The present invention provides a method of treating Alzheimer's disease using a novel compound of formula (I), wherein X is phenyl or substituted phenyl; Y is phenyl, substituted phenyl, pyridyl, or substituted pyridyl. Also provided is a method of inhibiting the aggregation of amyloid proteins using a compound of formula (I) and a method of imaging amyloid deposits using isoindoline derivatives.</p> |
申请公布号 |
NO20015992(A) |
申请公布日期 |
2002.02.06 |
申请号 |
NO20010005992 |
申请日期 |
2001.12.07 |
申请人 |
WARNER-LAMBERT CO |
发明人 |
AUGELLI-SZAFRAN, CORINNE ELIZABETH;LAI, YINGJIE;SAKKAB, ANNETTE THERESA;WALKER, LARY CRASWELL |
分类号 |
A61K31/4035;A61K31/4178;A61K49/06;A61K51/04;A61P25/28;A61P43/00;C07D209/44;C07D401/12;C07D403/12;(IPC1-7):C07D209/44;A61K31/403 |
主分类号 |
A61K31/4035 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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