摘要 |
Methods are provided for altering levels of syadocan within a cell. The methods include enhancing syndacan expression via administration of growth factors, preventing suppression of syndecan expression via administration of anti-steroid agents, and altering syndecan biochemistry within the cell. The methods are used to induce or maintain cellular differentiation, and to decrease die growth of malignant cells. Application of the methods to the treatment of patients, including humans, is provided.
|
申请人 |
WARRI, ANNI MAIJA;AUVINEN, PETRI OLLI VILJAMI;JAAKKOLA, PANU MIKKO;JALKANEN, MARKKU TAPANI;LEPPA, SIRPA MARIANNE;MALI, MARKKU SAKARI;VIHINEN, TAPANI ANTERO;ALANEN-KURKI, LEENA MARIA |
发明人 |
WARRI, ANNI MAIJA;AUVINEN, PETRI OLLI VILJAMI;JAAKKOLA, PANU MIKKO;JALKANEN, MARKKU TAPANI;LEPPA, SIRPA MARIANNE;MALI, MARKKU SAKARI;VIHINEN, TAPANI ANTERO;ALANEN-KURKI, LEENA MARIA |