| 摘要 |
The present invention relates to a peptide having the amino acid sequence <table-cwu id="TABLE-US-00001"> <number>1</number> <table frame="none" colsep="0" rowsep="0" tabstyle="monospace"> <tgroup align="left" colsep="0" rowsep="0" cols="2"> <colspec colname="1" colwidth="133PT" align="left"/> <colspec colname="2" colwidth="84PT" align="left"/> <tbody valign="top"> <row> <entry></entry> </row> <row> <entry>Leu Thr Cys Leu Asn Cys Pro Glu Met Phe</entry> <entry></entry> </row> <row> <entry> 1 5 10</entry> </row> <row> <entry> </entry> </row> <row> <entry>Cys Gly Lys Phe Gln Ile Cys Arg Asn Gly</entry> </row> <row> <entry> 15 20</entry> </row> <row> <entry> </entry> </row> <row> <entry>Glu Lys Ile Cys Phe Lys Lys Leu His Gln</entry> </row> <row> <entry> 25 30</entry> </row> <row> <entry> </entry> </row> <row> <entry>Arg Arg Pro Leu Ser Trp Arg Tyr Ile Arg</entry> </row> <row> <entry> 35 40</entry> </row> <row> <entry> </entry> </row> <row> <entry>Gly Cys Ala Asp Thr Cys Pro Val Gly Lys</entry> </row> <row> <entry> 45 50</entry> </row> <row> <entry> </entry> </row> <row> <entry>Pro Tyr Glu Met Ile Glu Cys Cys Ser Thr</entry> </row> <row> <entry> 55 60</entry> </row> <row> <entry> </entry> </row> <row> <entry>Asp Lys Cys Asn Arg</entry> </row> <row> <entry> 65</entry> </row> </tbody> </tgroup> </table> </table-cwu> or alleles derived therefrom, or peptides containing essential parts of the peptide (I), to a process for the preparation thereof and the use thereof for producing a pharmaceutical for the treatment of diseases of which therapy is possible through inhibition of the alpha7-nACh receptor, in particular the treatment of cancer such as small cell lung carcinoma. |
