Naphthyl-substituted and anilide-substituted sulfonamides

摘要

Naphthyl and anilide-substituted sulphonamides of the general formula (I), processes for their preparation and their use as antiviral agents, in particular against cytomegaloviruses. Wherein; R1 and R2 are identical or different and represent hydrogen, formyl, phenyl or benzyl optionally substituted with one to three halogen atoms, or straight chain or branched alkyl or acyl can optionally be substituted by one to three substituents selected from halogen and hydroxyl; A, D, E and G are identical or different and represent hydrogen, halogen, nitro, cyano, hydroxyl, carboxyl, trifluromethyl, trifluoromethoxy or straight chain or branched alkyl, alkoxy or alkoxycarbonyl each having up to 5 carbon atoms; R3 represents straight chain or branched alkenyl having up to 6 carbons, or straight chain or branched or branched alkyl having up to 8 carbon atoms, which optionally carries an amino group optionally substituted by alkyl having up to 4 carbon atoms or by an amino protective group, or the alkyl is optionally identically or differently substituted one to 3 times by hydroxyl, cyano, halogen, azido, nitro, trifluoromethyl, carboxyl or phenyl which, for its part, can be identically or differently substituted up to 2 times by nitro, halogen, hydroxyl or by straight chain or branched alkyl or alkoxy having up to 4 carbon atoms, or R3 represents the Formula (II), (III), or (IV); R4 denotes hydrogen or a radical of the Formula (V); and X has the same meaning as R4.