发明名称 |
USE OF DERIVATIVES OF VALPROIC ACID AND 2-VALPROENIC ACID AMIDES FOR THE TREATMENT OF MANIA IN BIPOLAR DISORDER |
摘要 |
A method for the treatment of mania in bipolar disorder using derivatives of valproic acid and 2-valproenic acid amines having the following structures: wherein R1, R2, and R3 are independently the same or different and are hydrogen, a C1-C6 alkyl group, an aralkyl group, or an aryl group, and n is an integer which is greater than or equal to 0 and less than or equal 3, or a compound containing a valproic or a 2-valproenic moiety, as well as pharmaceutical compositions comprising these derivatives or compounds. |
申请公布号 |
WO0207677(A2) |
申请公布日期 |
2002.01.31 |
申请号 |
WO2001US23116 |
申请日期 |
2001.07.20 |
申请人 |
TEVA PHARMACEUTICAL INDUSTRIES, LTD.;YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW;TEVA PHARMACEUTICAL USA, INC.;SHIRVAN, MITCHELL;BIALER, MEIR |
发明人 |
SHIRVAN, MITCHELL;BIALER, MEIR |
分类号 |
A61P25/18;A61K31/16;A61K31/19 |
主分类号 |
A61P25/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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