发明名称 |
COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES. |
摘要 |
<p>Novel cyclohexanes of Formulas (I) and (II) <IMAGE> (I) <IMAGE> (II) are described herein. They inhibit the production of Tumor Necrosis Factor and are useful in the treatment of disease states mediated or exacerbated by TNF production; these compounds are also useful in the mediation or inhibition of enzymatic or catalytic activity of phosphodiesterase V.</p> |
申请公布号 |
GR3036853(T3) |
申请公布日期 |
2002.01.31 |
申请号 |
GR20010401717T |
申请日期 |
2001.10.09 |
申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
CHRISTENSEN, SIEGFRIED, BENJAMIN, IV;BENDER, PAUL, ELLIOT;FORSTER, CORNELIA, JUTTA |
分类号 |
C07D295/00;A61K31/12;A61K31/24;A61K31/275;A61K31/33;A61P11/06;A61P29/00;A61P37/08;C07C45/44;C07C45/51;C07C45/71;C07C47/47;C07C47/575;C07C49/603;C07C49/613;C07C49/753;C07C49/757;C07C233/56;C07C235/82;C07C251/42;C07C255/46;C07C255/54;C07C255/64;C07D213/00;C07D215/00;C07D233/00;C07D239/00;C07D257/00;C07D261/00;C07D263/00;C07D277/00;C07D307/00;C07D309/00;C07F7/08;(IPC1-7):A61K31/275;C07C255/50 |
主分类号 |
C07D295/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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