发明名称 |
USE OF THE INTERFERON RECEPTOR 2c POLYPEPTIDE CHAIN TO ENHANCE THE ANTI-GROWTH EFFECTS OF TYPE I INTERFERONS |
摘要 |
The present invention is directed towards a method of potentiating the anti-growth effects of type I interferon (IFN) on cells in a target cell population comprising increasing the number of functional IFNAR2c receptors on the surface of modified cells within the target cell population and then exposing the modified cells to a therapeutically effective amount of a type I IFN or by exposure to endogenously produced IFN.
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申请公布号 |
WO0207777(A1) |
申请公布日期 |
2002.01.31 |
申请号 |
WO2001US41412 |
申请日期 |
2001.07.26 |
申请人 |
SCHERING AKTIENGESELLSCHAFT;CROZE, ED;VOGEL, DAVID;RUSSEL-HARDE, DEAN |
发明人 |
CROZE, ED;VOGEL, DAVID;RUSSEL-HARDE, DEAN |
分类号 |
A61K48/00;A61K35/76;A61K38/00;A61K38/17;A61K38/21;A61K38/22;A61K45/00;A61P7/00;A61P9/10;A61P35/00;A61P35/02;A61P43/00;(IPC1-7):A61K48/00 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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