PROCESS FOR THE PREPARATION OF 2-AMINO ACIDS

摘要

A process for the preparation of 2-amino acids of the general formula [II]: RCH(NH2)COOH (wherein R is hydrogen, optionally substituted C1-6 alkyl, or the like), characterized by hydrolyzing a 2-aminonitrile of the general formula [I]: RCH(NH2)CN into a 2-amino acid of the general formula [II] in an aqueous solution containing a polybasic acid salt by the use of a biocatalyst exhibiting a nitrile-hydrolyzing activity.