INTERNAL STANDARDS AND CONTROLS FOR MULTIPLEXED ASSAY

摘要

Internal standards and controls are provided for detecting and/or compensating for sources of measurement error in multiplexed diagnostic and genetic assays. The internal standards include subsets of particles comprising ligand binding partner specific for analytes of interest, each subset having a different known amount of ligand binding partner. Internal controls include subsets of particles comprising ligand binding partner chosen to provide information relating to high-dose hook effects, dilutional linearity, interfering assay factors, or sample or reagent omission.