| 发明名称 |
3-(Substituted)-1-carba(dethia)-3-cephems and cephalosporins and a process for production therefor. |
| 摘要 |
<p>Cephalosporin and 1-carba(1-dethia)cephalosporin antibiotics substituted in the 3-position with, inter alia, alkyl, alkenyl and alkynyl, are provided via process comprising conversion of a cephalosporin or 1-carba(1-dethia)-3-cephem substituted in the 3-position with halogen or a sulfonyloxy ester with Pd(O) mediated alkylation with organostannanes.</p> |
| 申请公布号 |
GR3036781(T3) |
申请公布日期 |
2002.01.31 |
| 申请号 |
GR20010401642T |
申请日期 |
2001.10.03 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
COOK, GWENDOLYN KAY;MCDONALD, III, JOHN HAMPTON |
| 分类号 |
A61K31/435;A61K31/545;A61K31/546;A61P31/04;C07D463/00;C07D501/04;C07D501/20;C07D501/22;C07D501/24;C07D501/26;C07F7/18;(IPC1-7):A61K31/435;C07D471/04;A61K31/535 |
主分类号 |
A61K31/435 |
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