发明名称 |
Improved in vitro method, kits and reagents for screening for blood coagulation defects |
摘要 |
<p>In vitro photometric method for qualitative screening and quantitative determination of the functional activity of components of the Protein C anti-coagulant pathway of blood coagulation, comprising measuring the conversion rate of an exogenous substrate by an enzyme, the activity of which is related to the Protein C anticoagulant activity, in a blood sample of a human comprising coagulation factors and said exogenous substrate after at least partial activation of coagulation through the intrinsic, extrinsic or common pathway and triggering coagulation by adding calcium ions; and comparing said conversion rate with the conversion rate of a normal human blood sample determined in the same way, comprising adding further metal(s) ions to said sample; kits and reagents for use in said method. <IMAGE></p> |
申请公布号 |
GR3036865(T3) |
申请公布日期 |
2002.01.31 |
申请号 |
GR20010401728T |
申请日期 |
2001.10.11 |
申请人 |
CHROMOGENIX AB |
发明人 |
ROSEN, BERT STEFFEN;HALL, CHRISTINA MARIA YVONNE |
分类号 |
C12Q1/56;G01N33/86;(IPC1-7):C12Q1/56 |
主分类号 |
C12Q1/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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