摘要 |
<p>The present invention relates to a process for the genetic manipulation of myxobacteria, preferably of myxobacteria from the Sorangium/Polyangium group, which makes possible for the first time specific application of recombinant DNA techniques to this group of organisms. The industrial implementation of this process is primarily based on the preparation of recombinant DNA molecules which, by reason of their specific construction, are able to integrate genes or DNA sequences which, where appropriate, code for novel and desirable properties, with the aid of homologous recombination at sites, which are accurately defined by reason of the homologies present, within the bacterial genome, and on the insertion thereof into the myxobacterial cell.</p> |