发明名称 |
METHOD FOR MAKING, LOADING AND SEALING A CELL OR DRUG ENCAPSULATION DEVICE, AND SUCH A DEVICE |
摘要 |
A wet seal method and apparatus for use in biologically implantable containment devices, the devices adaptable for drug formulations or cell suspensions. A porous membrane, in a tubular configuration, is formed and can be configured as part of a closed cell-tight system for loading. During loading, the containment device membrane is wet, while the loading system remains cell-tight. The containment device is sealed through a combination of heat and pressure, while the system remains cell-tight. Sealing the containment device substantially or completely eliminates metabolic functioning of any organisms in the vicinity of the closure. The seal is formed by melting a thermoplastic material that is in contact with the membrane. The containment device is separated from the cell-tight loading system, which remains closed after separation.
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申请公布号 |
WO0164185(A3) |
申请公布日期 |
2002.01.31 |
申请号 |
WO2001US06196 |
申请日期 |
2001.02.26 |
申请人 |
GORE ENTERPRISE HOLDINGS, INC. |
发明人 |
NEWMAN, STEVEN, C.;KRAM, BRIAN, H.;HUBBARD, TERRY, A. |
分类号 |
A61K9/48;A61D7/00;A61F2/02;A61K9/00;A61K45/00;A61K47/32;A61K48/00;A61L27/00;A61L29/00;A61M37/00;(IPC1-7):A61F2/02 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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