发明名称 |
ALLERGENIC PROTEINS AND PEPTIDES FROM DOG DANDER AND USES THEREFOR |
摘要 |
Isolated nucleic acids encoding allergens of Canis familiaris, Canf I or Can f II, are disclosed. A cDNA encoding a peptide having a Can f I activity and a predicted molecular weight of about 19,200 daltons is also described. A cDNA encoding a peptide having Can f II activity and a predicted molecular weight of about 18,200 daltons is also disclosed. The nucleic acids can be used as probes to detect the presence of Can f I or Can f II nucleic acid in a sample or for the recombinant production of petides having a Can f I or Can f II activity. Peptides having a Can f I or Can f II activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to dog dander.
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申请公布号 |
US2002012963(A1) |
申请公布日期 |
2002.01.31 |
申请号 |
US19990374671 |
申请日期 |
1999.08.16 |
申请人 |
IMMULOGIC PHARMACEUTICAL CORPORATION |
发明人 |
MORGENSTERN JAY P.;BIZINKAUSKAS CHRISTINE B.;KONIECZNY ANDRZEJ;BRAUER ANDREW W. |
分类号 |
G01N33/53;A61K38/00;A61K39/35;A61K39/395;A61P37/08;C07K14/47;C12N1/21;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12R1/19;(IPC1-7):C07K17/00;C07K14/00;C07K1/00;C12N15/74;C12N15/70;C12N15/63;C12N15/00;C12N1/20;C12P21/06;C07H21/04;C07H21/02;C12N5/02;C12N5/00 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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