| 摘要 |
<p>The invention provides a protein (BSTP-Ras/Rerg) and polynucleotides which identify and encode BSTP-Ras. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. In addition, the invention provides methods for treating or preventing disorders of cell proliferation, particularly breast cancer, by administering a pharmaceutical composition comprising a polypeptide, polynucleotide, or antibody of the invention. The invention also provides methods of classifying diseases, particularly breast cancer, by detecting expression of BSTP-Ras or of a polynucleotide encoding BSTP-Ras, and of providing diagnostic, prognostic, and/or predictive information for a patient based on the detection and/or measurement of BSTP-Ras or of a gene that encodes BSTP-Ras or of a mutation in the BST-RAS/Rerg gene.</p> |
