| 发明名称 |
SUBSTITUTED 5-ALKYNYL PYRIMIDINES HAVING NEUROTROPHIC ACTIVITY |
| 摘要 |
The present invention relates to a series of novel substituted 5-alkynyl pyrimidines, pharmaceutical compositions which contain them, methods for the ir preparation, and their use in therapy, particularly in the treatment of neurodegenerative or other neurological disorders of the central and peripheral nervous systems, including age related cognitive disorders such a s senility and Alzheimer's disease, nerve injuries, peripheral neuropathies, a nd seizure disorders such as epilepsy.
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| 申请公布号 |
CA2416442(A1) |
申请公布日期 |
2002.01.31 |
| 申请号 |
CA20012416442 |
申请日期 |
2001.07.20 |
| 申请人 |
KRENITSKY PHARMACEUTICALS, INC. |
发明人 |
KELLEY, JAMES L.;KRENITSKY, THOMAS A.;BEAUCHAMP, LILIA |
| 分类号 |
C07D239/30;A61K31/505;A61K31/506;A61K31/5375;A61K31/5377;A61K31/661;A61P3/10;A61P25/00;A61P25/02;A61P25/08;A61P25/18;A61P25/28;C07D239/42;C07D239/46;C07D239/47;C07D239/48;C07D401/04;C07D405/04;C07F9/6512;(IPC1-7):C07D239/34;C07D239/38 |
主分类号 |
C07D239/30 |
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