发明名称 Use of an active agent for treatment of cancer
摘要 The invention relates to the use of an active agent, particularly an inhibitor, in treating cancer by influencing, preferably inhibiting the expression of matrix-metalloproteases. The targets for this active agent can especially relate to downstream regulators of the matrix-metalloprotease 9 (MMP-9) signal transduction pathway. According to the invention, expecially inhibitors of p38beta and p38gamma as also of mitogen-activated kinase kinase 6 (MKK6) and mitogen-activated kinase kinase 3 (MKK3) can be applied.
申请公布号 AU8763201(A) 申请公布日期 2002.01.30
申请号 AU20010087632 申请日期 2001.07.17
申请人 CHRISTIAN SIMON;HANS-PETER ZENNER 发明人 CHRISTIAN SIMON;HANS-PETER ZENNER
分类号 A61K45/00;A61K31/00;A61K31/4439;A61K38/00;A61K48/00;A61P35/00;A61P43/00 主分类号 A61K45/00
代理机构 代理人
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