| 发明名称 |
Pyrrolidine-2-carboxylic acid hydrazide derivatives for use as metalloprotease inhibitors |
| 摘要 |
The present invention relates to a pyrrolidine compound and pharmaceutically acceptable esters and/or salts thereof. The compounds are useful as inhibitors of metalloproteases, e.g. zinc proteases, particularly zinc hydrolases, and which are effective in treating disease states are associated with vasoconstriction of increasing occurrences. |
| 申请公布号 |
AU7639601(A) |
申请公布日期 |
2002.01.30 |
| 申请号 |
AU20010076396 |
申请日期 |
2001.07.11 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
JOHANNES AEBI;HENRIETTA DEHMLOW;ERIC ARGIRIOS KITAS |
| 分类号 |
A61K31/40;A61K31/401;A61K31/4025;A61K31/454;A61K31/455;A61K31/4709;A61K31/501;A61P3/10;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P11/06;A61P13/12;A61P15/00;A61P17/02;A61P25/00;A61P25/06;A61P27/02;A61P27/06;A61P31/04;A61P35/00;A61P37/06;C07D207/16;C07D207/263;C07D401/12;C07D403/06;C07D405/12;C07D409/12 |
主分类号 |
A61K31/40 |
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