发明名称 |
PROCESS FOR THE PREPARATION OF TRIFLUOROTHYMIDINE DERIVATIVES |
摘要 |
<p>5-trifluoromethyl-2,4-bis(trimethylsilyloxy)pyrimidi ne is reacted with a 2-deoxy- alpha -D-erythro-pentofuranosyl chloride derivative reacted in the absence or presence of a small amount of solvent to give a beta -form of 1-(2'-deoxy- beta -D-erythro-pentofuranosyl)-5-trifluoromethyl uracil derivative with a high selectivity.</p> |
申请公布号 |
EP1176150(A1) |
申请公布日期 |
2002.01.30 |
申请号 |
EP20010902834 |
申请日期 |
2001.02.09 |
申请人 |
MITSUI CHEMICALS, INC. |
发明人 |
UMETANI, HIDEKI;FUKAZAWA, NOBUYUKI;KOMATSU, HIRONORI |
分类号 |
C07H19/06;(IPC1-7):C07H19/073 |
主分类号 |
C07H19/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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