发明名称 Radioligand and binding assay
摘要 The present invention is directed to the radioligand compound, [<35>S]-radiolabeled (+)-N-[1'-(6-cyano-1,2,3,4-tetrahydro-2(R)-naphthalenyl)-3,4-dihydro-4(R)-hydoxyspiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]methanesulfonamide. Also within the scope of this invention is a method for identifying compounds that bind to the IKr channel, and may have antiarrhythmic activity.
申请公布号 AU7786301(A) 申请公布日期 2002.01.30
申请号 AU20010077863 申请日期 2001.07.10
申请人 MERCK AND CO., INC. 发明人 JOHN W. BUTCHER;DAVID A. CLAREMON;THOMAS M. CONNOLLY;DENNIS C. DEAN;JERZY KARCZEWSKI;KENNETH S KOBLAN;MATTHEW J. KOSTURA;NIGEL J. LIVERTON;DAVID G. MELILLO
分类号 G01N33/566;A61K51/04;C07D491/10;C07D491/107;C07D491/20;C07F7/18;C12N15/09;C12Q1/02;G01N33/58;G01N33/60;G01N33/68 主分类号 G01N33/566
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