发明名称 |
Regulation of gene expression using single-chain, monomeric, ligand dependent polypeptide switches |
摘要 |
The invention relates to single chain, monomeric polypeptide gene switches. The gene switches include ligand binding domains and at least one functional domain. Preferred functional domains are DNA binding domains. The invention also relates to methods regulating gene function using these switches |
申请公布号 |
AU7254401(A) |
申请公布日期 |
2002.01.30 |
申请号 |
AU20010072544 |
申请日期 |
2001.07.16 |
申请人 |
NOVARTIS AG;THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
ROGER BEERLI;ULRICH SCHOPFER;CARLOS F. BARBAS |
分类号 |
C12N15/09;C07K14/47;C07K14/72;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/63 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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