Process for the preparation of pyrazolo¬4,3-d pyrimidin-7-ones and intermediates thereof

摘要

A process is provided for the preparation of compounds of formula (I) herein comprising reacting a compound of formula (II), (III), (IV) or (V) in the presence of <->OR<3> and a hydroxide trapping agent or in the case of compounds of formula (IV) reacting in the presence of an auxiliary base and a hydroxide trapping agent (i.e. <->OR<3> is substituted by the auxiliary base), wherein X is a leaving group and R<1> to R<4> are as defined.