INDIVIDUAL SUBSTANCES SYNTHESIZED ON BASE OF CHEMICAL INTERACTION OF DISULFIDE-CONTAINING PEPTIDES WITH PURINE OR PYRIMIDINE BASE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND PREPARATIONS BASED ON THEREOF, METHODS OF THEIR USING FOR TREATMENT OF INFECTIOUS DISEASES AND PROPHYLAXIS OF COMPLICATIONS

摘要

medicine, pharmacy. SUBSTANCE: invention relates to development of medicinal agents based on active metabolites of peptide and nucleoside-nucleotide nature. Invention proposes novel compounds synthesized on the base of chemical interaction of oxidized glutathione (G-SS-G) with derivatives of purine or pyrimidine bases; pharmaceutical compositions and preparations based on thereof eliciting antiviral, antibacterial, immunomodulating and hepatoprotective effects; methods of treatment and prophylaxis of infectious diseases. EFFECT: development of novel medicinal agents and methods of their using for treatment and prophylaxis of infectious diseases of different etiology. 89 cl, 42 dwg, 60 tbl