PEPTIDE FRUCTOSE AND COMPLEX THEREOF WITH BINDING PROTEIN

摘要

It is intended to provide an antibody specific to HbA1c, antibody-producing cells capable of supplying the antibody in a stable state in future too, and a method of surely constructing the antibody-producing cells without any probability factors. A method which comprises fusing mouse spleen cells, which have been sensitized with an immunogen composed of a compound containing the following structural formula (I) and a binding protein, with a myeloma-origin cell line, obtaining monoclonal antibody-producing cells by cloning, and then purifying and acquiring the monoclonal antibody produced by these cells in the culture supernatant (I).