摘要 |
<p>An integrated composite electrode for measuring an electrophysiologic characteristic of a biological sample comprising microelectrodes arranged in a first area on a substrate and reference electrodes arranged in a second area on the substrate and including one or more stimulating reference electrodes for imparting electric signals to the microelectrodes. Preferably, the reference electrodes include one or more measuring reference electrodes for measuring electric signals from the microelectrodes, and the stimulating reference electrodes are insulated from the measuring reference electrodes in an electric circuit way. Preferably, the second area is provided at a distance from the periphery of the first area and encompasses it.</p> |