摘要 |
<p>The invention provides isolated nucleic acids molecules, designated GEF32529 nucleic acid molecules, which encode novel human guanine nucleotide exchange factor (GEF) molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing GEF32529 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a GEF32529 gene has been introduced or disrupted. The invention still further provides isolated GEF32529 polypeptides, fusion polypeptides, antigenic peptides and anti-GEF32529 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.</p> |