SILDENAFIL CITRATE SOLID DISPERSIONS HAVING HIGH WATER SOLUBILITY

摘要

Solid dispersions of sildenafil citrate and certain highly water soluble sugars are provided, which solid dispersions significantly increase the wate r solubility of sildenafil citrate. Methods for preparing highly water soluble solid dispersions of the present invention facilitate the incorporation of sildenafil citrate into new sildenafil citrate containing dosage forms which were heretofore impractical. A method for improving and/or enhancing the sexual response in animals, particularly humans, by administering such new sildenafil citrate containing dosage forms is also provided.