发明名称 |
Method for preparing solid delivery system for encapsulated and non-encapsulated pharmaceuticals |
摘要 |
A method for producing a delivery system for transporting pharmaceuticals and other ingredients in a chewable and palatable form is provided. The delivery system comprises a lipid source in which drug actives are homogeneously suspended to form a high solids suspension which can be solidified and molded into an oral dosage form. The lipid source provides an external phase comprising the carrier for the suspension and also provides a hydrophobic film which continuously coats the hydrophilic drug actives and other ingredients. The suspension exhibits pseudoplastic and thixotropic properties which enable it to suspend a large volume of particles relative to the lipid source. The drug particles may be pre-encapsulated before mixing in with the suspension, which provides taste-masking and controlled release qualities to the products formed from the delivery system.
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申请公布号 |
US6340471(B1) |
申请公布日期 |
2002.01.22 |
申请号 |
US19990476483 |
申请日期 |
1999.12.30 |
申请人 |
KERSHMAN ALVIN;SHEAR JEFF L. |
发明人 |
KERSHMAN ALVIN;SHEAR JEFF L. |
分类号 |
A61K9/00;A61K9/16;A61K9/20;A61K9/50;(IPC1-7):A61K9/16 |
主分类号 |
A61K9/00 |
代理机构 |
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地址 |
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