METHOD FOR PRODUCING POLY-3-HYDROXYBUTYRIC ACID

摘要

PROBLEM TO BE SOLVED: To provide a method for continuously producing a high-molecular weight poly-3-hydroxybutyric acid. SOLUTION: This method comprises continuously cultivating methanol- assimilative bacteria having the ability to accumulate poly-3-hydroxybutyric acid in its microbial cells, using methanol as the carbon source, in a single culture tank while keeping mean residence time >=20 h, methanol concentration in the culture liquid <=10 ppm, nitrogen source concentration calculated as nitrogen atom <=10 ppm.