A sequencing methodology is disclosed that allows a single DNA or RNA molecu le or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
申请公布号
CA2415897(A1)
申请公布日期
2002.01.17
申请号
CA20012415897
申请日期
2001.07.09
申请人
VISIGEN BIOTECHNOLOGIES, INC.
发明人
GAO, XIAOLIAN;TU, SHIAO-CHUN;WILLSON, RICHARD;BRIGGS, JAMES M.;HARDIN, SUSAN H.
